Duke Office for Research & Innovation
2022-2023 Annual Report
Letter from the Vice President for Research
I am pleased and proud to share Duke Research & Innovation’s achievements from the past year in our 2022-23 annual report. This is merely a glimpse of the vast array of discovery and commercialization efforts of our faculty and students, none of which could have happened without the dedicated partnership of our research staff.
Our scholars and researchers continue to build new understandings of the human condition and enrich our future through their creative output. We continue to produce new knowledge, treatments, technologies and materials to make the world healthier and more sustainable.
Duke remains a top-tier research university and holds an international reputation for collaborative, insightful exploration that benefits from the relatively boundary-free research environment on our campus and around the world. We are proud to share that Duke performed $1.39 billion worth of research, with more than $901 million coming from federal grants. (FY 2022 HERD data)
Duke scholars are creating new vaccines against coronaviruses, influenza and HIV, and they are looking for new therapies deep within the cell by learning how to read and write the fundamental language of RNA. And they are developing scientific and policy solutions to the challenges of our changing climate.
These are just a few of our forward-looking pursuits, which taken together, amount to a powerful engine for North Carolina’s economy. Duke spawned 15 new companies based on our innovations in the last year and directly supported more than 13,000 workers involved in our research enterprise.
Thank you for another great year and for your support of Duke Research & Innovation.
Jennifer Lodge, Ph.D.
Vice President for Research & Innovation
Professor of Molecular Genetics and Microbiology
By the Numbers
Duke University surpassed $1.39 billion in total research expenditures in fiscal year 2022-23 with more than $901 million in federally sponsored research spending. Duke’s Office for Translation & Commercialization (OTC) helped launch 15 new startups and 325 New Invention Disclosures were submitted. Duke research faculty were awarded 12,364 grants and authored 11,390 publications.
in total research expenditures
in federally sponsored research
Value of proposals
Number of awards
Value of awards
Faculty Researcher Accomplishments
Honors and awards
Translation and commercialization
New invention disclosures
U.S. patents issued
National Academy of Medicine
National Academy of Engineering
American Association for the Advancement of Science
American Academy of Arts and Sciences
National Academy of Inventors
Howard Hughes Medical Institute
Cell Biologist Chantell Evans is one of 31 inaugural Freeman Hrabowski Scholars receiving a five-year scholarship providing full salary, benefits, a research budget, and scientific equipment.
Chan-Zuckerberg Science Diversity Leadership Awards
Three Duke scholars were among 25 awardees nationally for $1.15 million over five years for promoting diversity, equity and inclusion in their fields.
Alex Gallimore, PhD, an engineer who has studied plasma propulsion for long-range space travel, has been named Provost. As chief academic officer of the university, he oversees the university’s academic mission, with broad responsibility for leading Duke’s schools and institutes, admissions, financial aid, libraries and information technology.
Center for Excellence in Regulatory Science and Innovation (CERSI)
The US Food and Drug Administration granted $50 million to create the center, a collaboration between Duke, UNC Chapel Hill, NC State University and NC Central University. It will provide infrastructure and tools to shorten the drug and device development process and advance public health.
The UCLA-Duke National Center for Child Traumatic Stress
The U.S. Substance Abuse and Mental Health Services Administration has provided $40 million over five years to improve care and access for children and their families who have experienced trauma.
Superfund Research Center
The National Institute of Environmental Health Sciences (NIH) awarded an $11.7 Million, 5-year renewal grant to support five research projects.
Schiff Family Humanities Fund
A Duke alumni couple made a $10 million gift to advance the humanities. It amplifies an endowment established by Beth York Schiff ’81, J.D.’85 and Jim Schiff ’81 in 2010 to support students and faculty pursuing humanistic studies.
Commercialization helps Duke’s innovations benefit humanity, and our highly successful and burgeoning Office of Translation and Commercialization is leading that charge.
Centaur Bio is developing technology that enhances the delivery of drugs and other compounds to parts of the body that are difficult to reach, such as the brain.
Confluence Water Advisors
Confluence Water Advisors is commercializing a first-of-a-kind database built up from rates published by water utilities across the nation that can be used by industry to plan a variety of water service projects to support sustainability and equity.
Lux One TechnologY
Lux One Technology is developing endoscopic imaging systems to visualize individual cells in a living patient.
Metabosensor is developing a device that integrates metabolomics data for the study of drug effects to enable precision medicine.
Paxos Medical is developing a neuromodulation device to treat non-obstructive urinary retention, also called underactive bladder.
Piximune Therapeutics is developing a novel class of antibodies to upregulate innate neuroprotective mechanisms to treat a broad range of degenerative conditions of the retina, including dry age-related macular degeneration.
Spoolyard is developing an interactive platform for creating, remixing, and sharing audiovisual experiences.
Vimana, the first startup out of a collaboration with health records software company nference, is developing combination approaches to treating gliomas and other central nervous system cancers.