Duke Office for Research & Innovation

2022-2023 Annual Report



Letter from the Vice President for Research

I am pleased and proud to share Duke Research & Innovation’s achievements from the past year in our 2022-23 annual report. This is merely a glimpse of the vast array of discovery and commercialization efforts of our faculty and students, none of which could have happened without the dedicated partnership of our research staff.

Our scholars and researchers continue to build new understandings of the human condition and enrich our future through their creative output. We continue to produce new knowledge, treatments, technologies and materials to make the world healthier and more sustainable.

Duke remains a top-tier research university and holds an international reputation for collaborative, insightful exploration that benefits from the relatively boundary-free research environment on our campus and around the world. We are proud to share that Duke performed $1.39 billion worth of research, with more than $901 million coming from federal grants. (FY 2022 HERD data)

Duke scholars are creating new vaccines against coronaviruses, influenza and HIV, and they are looking for new therapies deep within the cell by learning how to read and write the fundamental language of RNA. And they are developing scientific and policy solutions to the challenges of our changing climate.

These are just a few of our forward-looking pursuits, which taken together, amount to a powerful engine for North Carolina’s economy. Duke spawned 15 new companies based on our innovations in the last year and directly supported more than 13,000 workers involved in our research enterprise.

Thank you for another great year and for your support of Duke Research & Innovation.


Jenny Lodge

Jennifer Lodge, Ph.D.

Vice President for Research & Innovation

Professor of Molecular Genetics and Microbiology

By the Numbers

Duke University surpassed $1.39 billion in total research expenditures in fiscal year 2022-23 with more than $901 million in federally sponsored research spending. Duke’s Office for Translation & Commercialization (OTC) helped launch 15 new startups and 325 New Invention Disclosures were submitted. Duke research faculty were awarded 12,364 grants and authored 11,390 publications.

Research Expenditures

$1.39 Billion

in total research expenditures

$901 Million

in federally sponsored research



Proposals submitted

$5.12 Billion

Value of proposals



Number of awards

$1.37 Billion

Value of awards

Faculty Researcher Accomplishments




Honors and awards



Translation and commercialization


New invention disclosures


New startups


U.S. patents issued

Faculty Recognition

National Academy of Medicine


Nicole Calakos, MD, PhD

Professor of neurology and Lincoln Financial Group Distinguished Professor of Neurobiology 

Scholars Profile

National Academy of Engineering


Gabriel G. Katul, PhD

Paul M. Gross Distinguished Professor of Hydrology and Micrometeorology

Scholars Profile

American Association for the Advancement of Science


Gerard C. Blobe MD, PhD

Cancer Scientist and Professor of Medicine 

Scholars Profile

Yiran Chen, PhD

Computer Scientist and John Cocke Distinguished Professor of Electrical and Computer Engineering

Scholars Profile

Steven B. Haase, PhD

Professor of Biology

Scholars Profile

American Academy of Arts and Sciences


Abdullah T. Antepli, MDiv

Religious Scholar and Associate Professor of the Practice of Public Policy, Sanford School of Public Policy, and Associate Professor of the Practice of Interfaith Relations, Divinity School. 

Scholars Profile

Kenneth A. Dodge, PhD  

Child Psychologist and William McDougal Professor of Public Policy, Sanford School of Public Policy, and Professor of Psychology and Neuroscience, Trinity College of Arts & Sciences.  

Scholars Profile

Amy S. Gladfelter, Ph.D. 

Cell Biologist and Professor of Cell Biology, Howard Hughes Medical Institute Investigator 


Scholars Profile

Margaret Sullivan, MS

Journalist and Jack and Pamela Egan Visiting Professor in Journalism and Public Policy, Sanford School of Public Policy.  

Scholars Profile

National Academy of Inventors


Matthew Becker, PhD 

Hugo L. Blomquist Distinguished Professor of Chemistry and Professor of Mechanical Engineering & Materials Science

Scholars Profile

Charles Gersbach, PhD

John W. Strohbehn Distinguished Professor of Biomedical Engineering; 

Scholars Profile

Warren Grill, PhD 

Edmund T. Pratt, Jr. School Distinguished Professor of Biomedical Engineering. 

Scholars Profile

Howard Hughes Medical Institute

Cell Biologist Chantell Evans is one of 31 inaugural Freeman Hrabowski Scholars receiving a five-year scholarship providing full salary, benefits, a research budget, and scientific equipment.


Chantell S. Evans, PhD

Assistant Professor of Cell Biology

Scholars Profile

Chan-Zuckerberg Science Diversity Leadership Awards

Three Duke scholars were among 25 awardees nationally for $1.15 million over five years for promoting diversity, equity and inclusion in their fields. 


Lawrence David, PhD  

Associate Professor of Molecular Genetics and Microbiology

Scholars Profile

Chantell Evans, PhD 

Assistant Professor of Cell Biology

Scholars Profile

Gustavo Silva, PhD 

Assistant Professor of Biology

Scholars Profile

New Leadership



Alex Gallimore, PhD, an engineer who has studied plasma propulsion for long-range space travel, has been named Provost. As chief academic officer of the university, he oversees the university’s academic mission, with broad responsibility for leading Duke’s schools and institutes, admissions, financial aid, libraries and information technology.

Read the full announcement

Executive Vice President for Health Affairs 

Mary Klotman, MD adds this title along with continuing to serve as dean of the School of Medicine. 

Read the announcement

Vice President and Vice Provost for Climate and Sustainability 

Toddi Steelman, PhD moved from Stanback Dean of the Nicholas School to overseeing the Duke Climate Commitment and the Office of Climate and Sustainability.  

Read the announcement

Dean of the Nicholas School  

Lori Bennear, PhD will serve a two-year term as Stanback Dean of the Nicholas School of the Environment.

Read the announcement

Awarded Funding

Major grants and gifts propel Duke’s research forward. 

Center for Excellence in Regulatory Science and Innovation (CERSI) 

The US Food and Drug Administration granted $50 million to create the center, a collaboration between Duke, UNC Chapel Hill, NC State University and NC Central University. It will provide infrastructure and tools to shorten the drug and device development process and advance public health. 

The UCLA-Duke National Center for Child Traumatic Stress  

The U.S. Substance Abuse and Mental Health Services Administration has provided $40 million over five years to improve care and access for children and their families who have experienced trauma. 

Superfund Research Center 

The National Institute of Environmental Health Sciences (NIH) awarded an $11.7 Million, 5-year renewal grant to support five research projects. 

Schiff Family Humanities Fund 

A Duke alumni couple made a $10 million gift to advance the humanities. It amplifies an endowment established by Beth York Schiff ’81, J.D.’85 and Jim Schiff ’81 in 2010 to support students and faculty pursuing humanistic studies. 


Commercializing Research

Commercialization helps Duke’s innovations benefit humanity, and our highly successful and burgeoning Office of Translation and Commercialization is leading that charge.

In FY 2023, Duke scholars disclosed 325 inventions, and launched 15 new startup companies with help from OTC. Our commercialization efforts are making a difference.



Calidar is using X-ray diffraction to create “4D mammography,” that adds structural tissue information at the molecular level to further enhance early breast cancer detection.


Centaur Bio

Centaur Bio is developing technology that enhances the delivery of drugs and other compounds to parts of the body that are difficult to reach, such as the brain.


Confluence Water Advisors

Confluence Water Advisors is commercializing a first-of-a-kind database built up from rates published by water utilities across the nation that can be used by industry to plan a variety of water service projects to support sustainability and equity.



Coprata is developing a non-invasive and hands-free  “smart toilet” technology that easily, safely and discreetly tracks a person’s health by monitoring their feces.



Eydisbio is developing small molecule therapies for the treatment of autoimmune and inflammatory diseases that are driven by aberrant inflammatory processes.



Lullabee is developing a smart crib mattress that teaches children to become better sleepers.


Lux One TechnologY

Lux One Technology is developing endoscopic imaging systems to visualize individual cells in a living patient.



Metabosensor is developing a device that integrates metabolomics data for the study of drug effects to enable precision medicine.


Navi Co.

Navi Co. is developing digital workflow technology for managing the coaching of entrepreneurs.


Paxos Medical

Paxos Medical is developing a neuromodulation device to treat non-obstructive urinary retention, also called underactive bladder.


Piximune Therapeutics

Piximune Therapeutics is developing a novel class of antibodies to upregulate innate neuroprotective mechanisms to treat a broad range of degenerative conditions of the retina, including dry age-related macular degeneration.



Spoolyard is developing an interactive platform for creating, remixing, and sharing audiovisual experiences.


Torque Bio

Torque Bio is developing circular mRNA expression systems for gene therapy.



Vimana, the first startup out of a collaboration with health records software company nference, is developing combination approaches to treating gliomas and other central nervous system cancers.


VivaMed NMDA Solutions

VivaMed NMDA Solutions is developing a novel antidepressant called rapastinel into an opioid use disorder treatment.

Duke Science and Technology New Faculty

Jose Ramon Conejo-Garcia 

Instructor in the Department of Integrative Immunobiology, School of Medicine 
Member of the Duke Cancer Institute 

Amy Susanne Gladfelter 

Instructor in the Department of Cell Biology, School of Medicine 
Member of the Duke Cancer Institute