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Infiltrating an Ovary

What might look like a green gumdrop or strands of red tinsel is actually a dense network of nerves forming within a developing mouse ovary. In a study led by Duke cell biology professor Blanche Capel, co-authors Jennifer McKey, Corey Bunce and colleagues show that nerves make their way into mouse gonads that are on their way to becoming future ovaries, but not into future testes, where nerves are restricted to the surface. The results shed light on how differences in nerve and blood supply help transform the same groups of cells in developing embryos into either male or female organs.