CABC Seminar: "The Struggle Is Real: The Role of Insular Cortex Circuitry in Stress Response and Alcohol Abstinence"

Samuel Centanni


Vahaba, Daniel


event sponsored by

Duke Institute for Brain Sciences (DIBS) &

Center for the Study of Adolescent Risk and Resilience (C-StARR), Center on Addiction and Behavior Change, and Department of Psychiatry and Behavioral Sciences


CABC Seminar Series


Samuel Centanni, PhD (Wake Forest University)

Neurobiology of stress and alcohol use disorder Stress and negative emotional states are often cited as one of the major factors in initiating a substance use disorder. These same feelings can drive cravings and relapse in recovering individuals, highlighting the gripping relationship between addiction and negative affect. What are the brain circuits regulating affective behavior and how does dysfunction in these circuits drive relapse? The overall aim of the Centanni Lab is to address these questions by taking an innovative, unbiased approach to delineate the complex neuronal control networks governing negative affect associated with stress and alcohol use disorder (AUD).


Medicine, Natural Sciences, Lecture/Talk, Panel/Seminar/Colloquium, and Research