How does the DUHS CRU/IRB review process work?

Campus protocols that utilize Duke Health patients or resources are submitted to the DUHS IRB using the eIRB system. Once submitted, the study is pre-reviewed to ensure a complete and streamlined package for final IRB review. This initial review is typically conducted by the Clinical Research Units (CRUs)— clinical department-based review units in the SOM—and focuses on scientific integrity, financial accountability, regulatory compliance, and overall quality. However, depending on the nature of the proposed work, a CRU may not be the appropriate operational home for all Campus-based studies.