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mouse fibroblasts

Deadly Emoticons

Living connective tissue cells called fibroblasts taken from an embryonic mouse glow under the microscope to indicate that the CALM-AF-10 gene is active within them. Duke pediatric cancer researcher Daniel Wechsler's team has identified the gene as part of a signaling sequence that can make cells immortal and lead to aggressive forms of leukemia. The discovery, which was featured on the cover of the journal Blood in June, points to a possible new therapeutic attack on leukemia.